N-palmitoylethanolamine: Biochemistry and new therapeutic opportunities.
PEA has been emerging as an important analgesic, anti-inflammatory and neuroprotective mediator, acting at several molecular targets in both central and sensory nervous systems as well as immune cells.
PEA significantly reduced the degree of spinal cord inflammation and tissue injury and apoptosis [nerve cell death]. Moreover, PEA treatment ameliorated [improved] the recovery of motor limb function.